Nevertheless, a demons meigs syndrome or a demons pseudosyndrome should be suspected when faced with a negative cytologic analysis of the ascitic and pleural effusion and no peritoneal implant on ctscan. A 48yearold perimenopausal woman presented with a long history of 810 years of abdominal distension. Pdf we report a rare case of pseudomeigs syndrome caused by ovarian metastasis from sigmoid. Meige syndrome genetic and rare diseases information. Meigs proposed limiting the diagnosis of meigs syndrome to benign and solid ovarian tumours with ascites and pleural effusion, and with the condition that removal of the tumour cures the patient without recurrence. Mar 24, 2016 meigs syndrome is defined as the triad of benign ovarian tumor with ascites and pleural effusion that resolves after resection of the tumor. History in 1934, salmon described the association of. Direct url citations appear in the printed text and are provided in the html and pdf versions of this article on the journals website. Meigs syndrome usually occurs in postmenopausal women and resolves following removal of the. This article is an openaccess article which was selected by an inhouse editor. Meigs syndrome megz, avoid the incorrect forms meig and meigs. Pdf meigs syndrome is a rare condition, occurring in less than 1% of ovarian tumors and has the characteristic. The demons meigs syndrome should usually be evoked in case of presence of a typical triad.
Demonsmeigs syndrome definition of demonsmeigs syndrome. The medical treatment of individuals with meigs syndrome is mostly intentional to offer relief that symptomatic of pleural effusion and ascites by means of therapeutic paracentesis which is a needle. Meige syndrome nord national organization for rare disorders. Meigs syndrome is defined as the coexistence of benign ovarian.
Unlike ovarian malignancies, meigs syndrome involves a benign. The more frequently observed type of ovarian tumor is the fibroma. Majzalin found that 65% of pleural effusions were right. These include various gynecological disorders of the uterus such as endometrial tumor, sarcoma, leiomyoma pseudomeigs syndrome. Meigs syndrome and pseudomeigs syndrome both presents with hydrothorax and ascites. Meigs syndrome is named after joe vincent meigs, an american gynecologist who defined meigs syndrome as the presence of ascites, hydrothorax, association with benign ovarian tumor. Meigs syndrome not to be confused with meige syndrome or meige diseasein medicine, meigs syndrome, also meigs syndrome or demons meigs syndrome, is the triad of ascites, pleural effusion, and benign ovaria. Meigs syndrome may mimic other conditions, since it is tumor arising from ovaries, pathology of any organs present in the abdomen may show a similar set of symptoms. When omd is combined with blepharospasm, it may be referred to as meiges.
Longterm survival in pseudomeigs syndrome caused by ovarian. Pseudo meigs syndrome refers to a clinical syndrome of pleural effusion, ascites associated with an ovarian tumor that is not a fibroma or a fibromalike tumor. The letter and case report of neustadt and levy, hemorrhagic pleural effusion in meigs syndrome 204. A pseudo case of atypical pseudomeigs syndrome article pdf available in indian journal of cancer 483. Pseudomeigs syndrome caused by gastric cancer with metastatic ovarian tumors is very rare. Pdf pleural effusion in meigs syndrometransudate or. Demonsmeigs syndrome is characterized by the presence of a. Approximately 1% of these are associated with meigs syndrome. Meigs syndrome is defined as the triad of benign ovarian tumor with ascites and pleural effusion that resolves after resection of the tumor. Pdf clinical experience of pseudomeigs syndrome due to colon. Meigss syndrome is the combination of ovarian fibroma. Get a printable copy pdf file of the complete article 1. Meige syndrome genetic and rare diseases information center.
Pseudomeigs syndrome is similar to meigs syndrome, except that the ovarian tumor may be malignant rather than benign. Entities that have been reported to result in pseudo meigs syndrome include. Ovarian fibromas constitute the majority of the benign tumors. Demonsmeigs syndrome indicates the association of a rightsided pleural effusion with ascites and a large ovarian. Dec, 2016 pseudomeigs syndrome is characterised by pleural effusion, ascites and benign ovarian tumours other than fibromas as described by meigs. Meigs syndrome is defined as the triad of benign ovarian tumor with ascites. Supplemental digital content is available for this article.
Treatment of this syndrome is based on vascular filling, sedation. Ascites and hydrothorax associated with a benign ovarian tumor other than a fibroma is designated pseudo meigs syndrome. This condition was further subclassified into 2 categories. The medical treatment of individuals with meigs syndrome is mostly intentional to offer relief that symptomatic of pleural effusion and ascites by means of therapeutic paracentesis which is a needle drainage procedure for the peritoneal cavity, and thoracentesis which is an invasive procedure to remove fluid or air from the pleural space. Meigs syndrome is named after joe vincent meigs, an american obstetrician and gynaecologist 18921963, who reported a case series in 1937 and subsequently described the syndrome. Read more about symptoms, diagnosis, treatment, complications, causes and prognosis. This is known as meigs syndrome, a name first suggested by rhoads and terrel in 1937. The patient was radiologically followedup without the need for treatment. In medicine, meigs syndrome, also meigs syndrome or demons meigs syndrome, is the triad of ascites, pleural effusion, and benign ovarian tumor ovarian fibroma, fibrothecoma, brenner tumour, and occasionally granulosa cell tumour. Majzalin found that 65% of pleural effusions were rightsided as in our case. The effusion, which is usually large and on the right side, is formed when fluid moves from the abdomen to the pleural space through diaphragmatic defects. The evaluation of suspected hepatic hydrothorax is discussed separately. Pseudomeigs syndrome a term given by meigs is the same as true meigs syndrome, except that in the pseudomeigs syndrome the tumor may be in the ovary, tubes, uterus or round ligament. Meigs syndrome and pathogenesis of pleurisy and polyserositis.
Meigs syndrome is characteristically associated with ovarian fibroma whereas pseudomeigs syndrome is associated with any ovarian or pelvic tumors, other than ovarian fibroma. As tends to be the fate of authors who collect cases of various syndromes, somebody comes up with some that have been missed. Meigs syndrome resolves after the resection of the tumor. Once the tumor is removed, both ascites and pleural effusion resolves. A case of meigs syndrome with preceding pericardial. Meigs syndrome is defined as the presence of ascites and pleural effusion in association with a benign, usually solid ovarian tumor. Direct url citations appear in the printed text and are provided in the html and pdf. Dec 11, 2015 nonclassic meigs syndrome and demonsmeigs syndrome. Pseudomeigs syndrome is the coexistence of pleurisy. If you have problems viewing pdf files, download the latest version of adobe reader for language access assistance, contact the ncats public information officer genetic and rare diseases. In medicine, meigs syndrome, also meigs syndrome or demonsmeigs syndrome, is the triad of ascites, pleural effusion, and benign ovarian. Case of pseudomeigs syndrome caused by gastric cancer.
Pseudopseudo meigs syndrome in a patient with systemic lupus erythematosus. The meigs syndrome ms described in 1937 by meigs and cass was characterized by benign. Meigs syndrome is a rare syndrome that consists of a benign ovarian tumor. Meigs syndrome symptoms, complications, treatment, surgery. Ovarian fibroma represents 2 to 5% of ovarian tumor and out of this only 1 to 2% of cases present as meigs syndrome. Meigs syndrome is the triad of ovarian tumor chapter 205, ascites, and pleural effusion.
In the vast majority 8090% of cases, the primary tumor is an ovarian. Not to be confused with meige syndrome or meige disease. Elevated serum carbohydrate antigen 125 ca 125 levels in postmenopausal women with solid adnexal masses, ascites and pleural effusion are highly suggestive for malignant ovarian tumor. In the vast majority 8090% of cases, the primary tumor is an ovarian fibroma. Treatment of meigs syndrome consists of thoracentesis and paracentesis to drain off the excess fluid exudate, and unilateral salpingo.
Clinical communication to the editor volume 2, issue 11. Dystonia is a group of movement disorders that vary in their symptoms, causes, progression, and treatments. Laboratory and serological findings included chronic disease anemia, leukopenia, and diffuse hypergammaglobulinemia. Pdf meigs syndrome presenting with axillary vein thrombosis and. Aggressive treatment, including r0 resection, for this disease if. Amylaseproducing ovarian neoplasm with pseudomeigs syndrome and elevated pleural fluid amylase. Meigs syndrome, however, is a diagnosis of exclusion, only after ovarian carcinoma is ruled out. Polyserositis in a patient with active systemic lupus. Given the curative treatment of the disease, it is important to consider meigs syndrome in. Pdf pleural effusion in meigs syndrometransudate or exudate. Meigs syndrome is characteristically associated with ovarian fibroma whereas pseudomeigs. Feb 17, 2015 if you have problems viewing pdf files, download the latest version of adobe reader for language access assistance, contact the ncats public information officer genetic and rare diseases information center gard po box 8126, gaithersburg, md 208988126 tollfree. Meigs syndrome not to be confused with meige syndrome or meige diseasein medicine, meigs syndrome, also meigs syndrome or demonsmeigs syndrome, is the triad of ascites, pleural. A pseudo case of atypical pseudomeigs syndrome thaker d a.
The majority of cases usually resolve after surgical resection of the ovarian mass. Meigs syndrome is a triad of medical conditions where there is a benign ovarian tumor specifically an ovarian fibroma with ascites fluid accumulation in the abdominal cavity and pleural effusion fluid around the lungs in the pleural space. Meigs syndrome consists of a benign ovarian tumor accompanied by ascites and hydrothorax. Case of pseudomeigs syndrome caused by gastric cancerrelated metastatic ovarian tumor with prolonged survival. Meigs syndrome is a condition in which certain benign tumors of the ovary are associated with ascites and hydrothorax, resembling a malignant tumor with metastases. Links to pubmed are also available for selected references. The tumours may include those of the fallopian tube, uterus, round ligament, mature teratomas, struma ovarii or ovarian leiomyomas, as well as those originating in the colon, breast and stomach 4. Ovarian fibromas constitute the majority of the benign tumors seen in meigs syndrome.
A 40yearold woman was diagnosed with systemic lupus erythematosus sle 10 years ago, manifesting with edematous hands, raynaud phenomenon, livedo reticularis, arthralgiasarthritis of hand joints, and lymphadenopathy, without renal involvement. Nonclassic meigs syndrome and demonsmeigs syndrome. Meige syndrome nord national organization for rare. Elevated serum carbohydrate antigen 125 ca 125 levels in postmenopausal women with solid adnexal. This group of neurological conditions is generally characterized by involuntary muscle contractions that force the body into abnormal, sometimes painful, movements and. Fibromyoma or fibromalike tumor thecoma or granlosacell tumor of the ovary associated with hydroperitoneum and hydrothorax. Aug 08, 2019 meigs syndrome is defined as the triad of benign ovarian tumor with ascites and pleural effusion that resolves after resection of the tumor. Meigs syndrome is a strange clinical entity that is also considered to be an uncommon complication of fibroma of the female genital tract.
Pseudomeigs syndrome refers to ascites and pleural fluid secondary to any other pelvic or abdominal tumors not included in definition of demons meigs syndrome. Meige syndrome belongs to a group of disorders known as dystonia. Severe inflammation may be caused by hyperferritinemia of pseudopseudo meigs syndrome in lupus patients. The majority of cases usually resolve after surgical. The term nonclassic meigs syndrome was applied for patients with ascites and pleural effusion associated with benign ovarian. A 48yearold perimenopausal woman presented with a long history of 810 years of. It is actually a combination of two forms of dystonia, blepharospasm and oromandibular dystonia omd. The first report of this condition involved dame mary page, wife of sir gregory page, bunhill fields, england, who died in 1728, in her 56th year.
Demonsmeigs syndrome indicates the association of a rightsided pleural effusion with ascites and a large ovarian clinical presentation, diagnosis and management of cholesterol effusions view in chinese. Ovarian fibroma is the most common cause of meigs syndrome and constitutes approximately 2% to 5% of all surgically removed ovarian tumors. Full text full text is available as a scanned copy of the original print version. Meigs syndrome definition of meigs syndrome by medical. Meigs syndrome is defined as the presence of a benign ovarian tumor with pleural effusion and ascites that resolve. Pleural effusion in meigs syndrometransudate or exudate. Meigs syndrome describes the occurrence of a solid benign ovarian tumor, usually a fibroma, along with the presence of ascites and pleural effusions. Demons meigs syndrome indicates the association of a rightsided pleural effusion with ascites and a large ovarian. It is also known as brueghels syndrome and oral facial dystonia.
Pseudo meigs syndrome refers to a clinical syndrome of pleural effusion, ascites associated with an ovarian tumor that is not a fibroma or a fibromalike tumor pathology. The term nonclassic meigs syndrome was applied for patients with ascites and pleural effusion associated with benign ovarian, fallopian tube, or broad ligament tumors other than those included in the definition of classic meigs syndrome table table1. In these patients, pleural effusion and ascites typically disappear following oophorectomy. In 1934, salmon described the association of pleural effusion with benign pelvic tumors.
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